Kansas IDeA Network of Biomedical Research Excellence

Bridging Grant Recipients

Bridging Awards Yr 17

PI University Title
Asano, Katsura KSU The Role of Translational Control in Metabolic Stress Response
Gong, Maojun WSU High-Throughput Screening of Tumors Using Integrated Microfluidic Systems
Pritchard, Michele KUMC Role for Hyaluronan and Rhamm in Scarless Liver Repair
Santra, Santimukul PSU Activatable Nanotheranostics for MR Imaging and Treatment
Xiong, Yulan KSU Molecular Regulation of LRRK2 in Neurodegeneration
Zhao, Liqin KU Clusterin (APOJ) in Brain Mitochondria

Bridging Awards Yr 16

PI University Title
Lundquist, Erik KU-L ETR-1/CELF and alternative splicing in cell migration
Peterson, Blake KU-L Synergistic Antibody Conjugates
Tamura, Masaaki KSU Preclinical evaluations of a hyaluronan-cisplatin conjugate for the treatment of lung cancer
Tang, Liang KU-L Molecular mechanism of viral DNA injection into Gram-negative bacteria

Bridging Awards Yr 15

PI University Title
Bousfield, George WSU Purification of FSH Glycoforms and Glycoform-Selective Antibodies
Chen, Jianhan KSU Modulation of p53 structure and function by cancer-associated mutations
Chien, Jeremy KUMC FoxM1 Inhibition to Enhance Carboplatin Sensitivity
Dhillon, Navneet KUMC Impact of Opiate abuse on HIV-mediated Pulmonary Endothelial Dysfunction
DiTacchio, Luciano KUMC Lysine demethylase JARID1a in regulation of transcription factors CREB and ChREBP
Geiger, Paige KUMC Targeting estrogen receptor alpha in the prevention of insulin resistance and type II diabetes
Karanicolas, John KU-L Identifying stabilizers of p53 using pocket complementarity
Kumar, Rajendra KUMC Functional analysis of age-specific FSH analogs using genetically altered mice
Lundquist, Erik KU-L Identifying molecules that interact with the P2 domain of UNC-40/DCC
Zeng, Yong KU-L Integrated Digital Microfluidic Platforms for Next-Generation Glycomics
Zolkiewski, Michal KSU Molecular chaperones of Ehrlichia chaffeensis

Bridging Awards Yr 14

PI University Title
Lamb, Audrey KU-L Salicylate production in siderophore biosynthesis
Neufeld, Kristi KU-L Bridge-Activation of heat shock response to prevent inflammation-associated colon cancer
Petroff, Peggy KUMC Maternal Immunity to Shared Placenta/Tumor Antigens

Bridging Awards Yr 13

PI University Title
Hua, Duy H. KSU Inhibition of Glycogen Synthase Kinase 3Beta b Tricyclic Pyrones and Quinolines
Stanford, John KUMC Strength training and presymptomatic AMPK activity in SOD1-G93A rats
Tamura, Massaki KSU Nanoparticle-based prevention of malignant cancer metastasis
Vediyappan, Govindsamy KSU Candida albicans hyphal growth inhibition

Bridging Awards Yr 12

PI University Title
Berkland, Cory KU-L Targeted nanoscale antigen arrays for treating autoimmune diseases
Fong, Peying KSU CFTR regulation of thyroid transport
Gamblin, T. Chris KU-L Biochemical and in vivo determinants of tau toxicity
Soares, Michael KUMC Trophoblast Differentiation
Wangemenn, Philine KSU Organogenesis of the cochlea in mouse models of SLC26A4-related deafness
Xu, Liang KU-L Nanovectors targeting pancreatic cancer stem cells

Bridging Awards Yr 11

PI University Title
Hua, Duy H. KSU Counteraction of Alzheimer's Disease
Lillich, James KSU Novel Mechanisms of NSAID-Induced GI Toxicity
Staudinger, Jeff KUMC Inflammation, PXR Modification and Drug Disposition
Troyer, Deryl KSU Novel paradigm using monocytes with magnetic nanoparticles and SN-38 in melanoma

Bridging Awards Yr 10

PI University Title
Beeser, Alexander KSU Translational potential of Pak1 inhibitors for Type 2 neurofibromatosis
Neufeld, Kristi KU-L Musashi: A novel Wnt target controlled by tumor suppressor APC
Petroff, Brian KUMC Improving fertility in cancer survivors
Ward, Robert KU-L Tissue-specific growth control in Drosophila
Zolkiewska, Anna KSU Structure-Function Analysis of Breast Cancer-Associated Mutations in ADAM12

Bridging Awards Yr 9

PI University Title
Bruses, Juan KUMC Analysis of N-cadherin Signaling in Neurons
Christenson, Lane KUMC MicroRNA Regulation of Ovarian Function
Petroff, Peggy KUMC Maternal tolerance to fetal alloantigens: Bridging grant application
Shi, Jishu KSU Identification of the defensin receptor that regulates IL-1beta release
Tamura, Masaaki KSU Targeted gene therapy with AT2 receptor nanoparticles for lung adenocarcinoma

Bridging Awards Yr 8

PI University Title
Bruses, Juan L. KUMC Isolation and Characterization of Synaptogenic Proteins
Detamore, Michael KU-L High toughness hydrogels for cartilage tissue engineering
Takemoto, Delores J.  KSU Protein Kinase C in the Lens
Takemoto, Larry J.  KSU Lens Membrane in Relation to Human Cataractogenesis

Bridging Awards Yr 7

PI University Title
McCarson, Kenneth E. KUMC CNS Sites Where Estrogen Modulates Hyperalgesia

Bridging Awards Yr 6

PI University Title
Peterson, Kenneth R. KUMC Molecular Control of Fetal y-globlin Gene Expression - Selection of Transactivators
Takemoto, Larry KSU Passage of Ocular Proteins into the Lens
Wang, Li KUMC Crosstalk of Nuclear Receptor Signaling in Regulating Fatty Liver

Bridging Awards Yr 5

PI University Title
Buechner, Mathew KU-L Molecular Genetics of C. Elegans Renal Tubules
Lundquist, Erik KU-L Cytoskeletal Signaling and Axon Pathfinding in C. Elegans
Richter, Mark KU-L High-Throughput Screening Assays for Cancer Therapeutics

Bridging Awards Yr 4

PI University Title
All P& B funds were awarded to Pilot Grants.

Bridging Awards Yr 3

PI University Title
Asano, Katsura KSU Control of Translation Initiation in Fission Yeast
Rozell, Timothy KSU Bridging: Altered FSH Receptors in Bovine Ovaries

Bridging Awards Yr2

PI University Title
All P & B funds were awarded to Pilot Grants.

Bridging Awards Yr1

PI University Title
Bousfield, George WSU Carbohydrate Modulation of Gonadotropin Action
Kuczera, Kryzysztof KU-L Molecular Modeling of Calmodulin Oxidation